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· 1h 2m
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One in four patients currently being considered for life support withdrawal may actually be fully conscious, they just can't signal it. That single finding, from a landmark New England Journal of Medicine study, is the practical stakes behind one of the most philosophically rich conversations in this series. Dr. Christof Koch - former president of the Allen Institute for Brain Science, 25-year collaborator with Nobel laureate Francis Crick, and founder of the startup Intrinsic Powers - joins Craig Smith to discuss why the hard problem of consciousness remains unsolved, what integrated information theory predicts about which systems can and cannot be conscious, and why his own mystical experience three years ago shifted his view from physicalism toward idealism. The conversation is grounded throughout in empirical work: Koch explains how Intrinsic Powers uses brain complexity measurements - sending magnetic pulses into the brain and measuring the complexity of the electrical response - to detect consciousness in behaviorally unresponsive patients, providing clinical teams and families with one critical bit of information at the most consequential moment of their lives. The episode closes with Koch's most personal revelation: a mystical experience in which the boundary between self and world dissolved and he felt direct acquaintance with the idea that everything is ultimately mental, an experience he is careful to distinguish from supernatural claims, but which shifted his metaphysical view in ways he describes with unusual candor for a scientist of his standing. Subscribe to Eye on A.I. for weekly conversations with the people building and deploying the future of AI.
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